Abexinostat (PCI-24781)
Product Specifications
CAS Number
783355-60-2
Synonyms
CRA-024781
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CN (C) CC1=C (OC2=CC=CC=C21) C (=O) NCCOC3=CC=C (C=C3) C (=O) NO
Molecular Formula
C21H23N3O5
Additionnal Information
Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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