Refametinib (RDEA119)
Product Specifications
CAS Number
923032-37-5
Synonyms
Bay 86-9766
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
COC1=CC (=C (C (=C1NS (=O) (=O) C2 (CC2) CC (CO) O) NC3=C (C=C (C=C3) I) F) F) F
Molecular Formula
C19H20F3IN2O5S
Additionnal Information
Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
Storage Conditions
2 years -80 in solvent
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