Vismodegib (GDC-0449)
Product Specifications
CAS Number
879085-55-9
Synonyms
GDC-0449
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
CS (=O) (=O) C1=CC (=C (C=C1) C (=O) NC2=CC (=C (C=C2) Cl) C3=CC=CC=N3) Cl
Molecular Formula
C19H14Cl2N2O3S
Additionnal Information
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
Storage Conditions
2 years -80 in solvent
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