PD153035 HCl
Product Specifications
CAS Number
183322-45-4
Synonyms
SU-5271 (AG1517) HCl , ZM 252868 HCl
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=CC=C3) Br) OC.Cl
Molecular Formula
C16H14BrN3O2.HCl
Additionnal Information
PD153035 HCl (SU-5271 HCl, AG1517 HCl, ZM 252868 HCl) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.
Storage Conditions
2 years -80 in solvent
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