Pictilisib (GDC-0941)
Product Specifications
CAS Number
957054-30-7
Synonyms
RG7321
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CS (=O) (=O) N1CCN (CC1) CC2=CC3=C (S2) C (=NC (=N3) C4=C5C=NNC5=CC=C4) N6CCOCC6
Molecular Formula
C23H27N7O3S2
Additionnal Information
Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold) . Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2.
Storage Conditions
2 years -80 in solvent
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