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Rapamycin

Product Specifications

CAS Number

53123-88-9

Synonyms

Sirolimus, AY-22989, NSC-2260804

Target

Autophagy

Applications

Autophagy

Smiles

CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) O) C) C) O) OC) C) C) C) OC

Molecular Formula

C51H79NO13

Additionnal Information

Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.

Storage Conditions

2 years -80 in solvent

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