Rapamycin
Product Specifications
CAS Number
53123-88-9
Synonyms
Sirolimus, AY-22989, NSC-2260804
Target
Autophagy
Applications
Autophagy
Smiles
CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) O) C) C) O) OC) C) C) C) OC
Molecular Formula
C51H79NO13
Additionnal Information
Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
Storage Conditions
2 years -80 in solvent
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