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Nilotinib

Product Specifications

CAS Number

641571-10-0

Synonyms

AMN-107

Target

Bcr-Abl

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C=C (C=C1) C (=O) NC2=CC (=CC (=C2) C (F) (F) F) N3C=C (N=C3) C) NC4=NC=CC (=N4) C5=CN=CC=C5

Molecular Formula

C28H22F3N7O

Additionnal Information

Nilotinib is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.

Storage Conditions

2 years -80 in solvent

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