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PD184352 (CI-1040)

Product Specifications

CAS Number

212631-79-3

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

C1CC1CONC (=O) C2=C (C (=C (C=C2) F) F) NC3=C (C=C (C=C3) I) Cl

Molecular Formula

C17H14ClF2IN2O2

Additionnal Information

PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis.

Storage Conditions

2 years -80 in solvent

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