What is the catalog number for Bosutinib?

The catalog number for Bosutinib is S1014-10mg.

What sizes are available for Bosutinib?

Bosutinib is available in the following size(s): 10 mg.

Is Bosutinib in stock?

Bosutinib is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Bosutinib?

Bosutinib is requires dry ice shipping.

Who manufactures Bosutinib?

Bosutinib is manufactured by Bimake.

What is the estimated delivery time for Bosutinib?

Estimated delivery time for Bosutinib is approximately 15 business day(s), depending on your location.

Bosutinib

Product Specifications

CAS Number

380843-75-4

Synonyms

SKI-606

Target

Src

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) CCCOC2=C (C=C3C (=C2) N=CC (=C3NC4=CC (=C (C=C4Cl) Cl) OC) C#N) OC

Molecular Formula

C26H29Cl2N5O3

Additionnal Information

Bosutinib is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.