Saracatinib (AZD0530)
Product Specifications
CAS Number
379231-04-6
Target
Src
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) CCOC2=CC3=C (C (=C2) OC4CCOCC4) C (=NC=N3) NC5=C (C=CC6=C5OCO6) Cl
Molecular Formula
C27H32ClN5O5
Additionnal Information
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q) . Saracatinib induces autophagy. Phase 2/3.
Storage Conditions
2 years -80 in solvent
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