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Veliparib (ABT-888)

Product Specifications

CAS Number

912444-00-9

Synonyms

NSC 737664

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

CC1 (CCCN1) C2=NC3=C (C=CC=C3N2) C (=O) N

Molecular Formula

C13H16N4O

Additionnal Information

Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3.

Storage Conditions

2 years -80 in solvent

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