MYCMI-6
Product Specifications
CAS Number
681282-09-7
Synonyms
NSC354961
Target
Myc
Applications
Apoptosis
Smiles
CCOC1=CC2=C (C3=C (C=C (C=C3) N=NC4=C (N=C (C=C4) N) N) N=C2C=C1) N
Molecular Formula
C20H19N7O
Additionnal Information
MYCMI-6 (NSC354961) is a potent and selective endogenous inhibitor of MYC:MAX protein interactions. MYCMI-6 blocks MYC-driven transcription and binds to the MYC bHLHZip domain with Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner with IC50 of <0.5 μM. MYCMI-6 induces apoptosis.
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