TBOPP
Product Specifications
CAS Number
1996629-79-8
Target
DOCK
Applications
Cell Cycle
Smiles
C1CCN (C1) S (=O) (=O) C2=CN (C (=O) C=C2) CC (=O) C3=CC=C (C=C3) C4=CC (=CC=C4) C (F) (F) F
Molecular Formula
C24H21F3N2O4S
Additionnal Information
TBOPP is a selective inhibitor of dedicator of cytokinesis (DOCK1, Dock180) that inhibits DOCK1-mediated Rac activation with IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with Kd of 7.1 μM. TBOPP exhibits anti-tumor activity.
Storage Conditions
3 years -20°C powder
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