Cucurbitacin IIb
Product Specifications
CAS Number
50298-90-3
Synonyms
CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A
Target
STAT
Applications
Apoptosis
Smiles
CC1 (C (C (CC2C1=CCC3C2 (C (=O) CC4 (C3 (CC (C4C (C) (C (=O) CCC (C) (C) O) O) O) C) C) C) O) O) C
Molecular Formula
C30H48O7
Additionnal Information
Cucurbitacin IIb (CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A) inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB, blocks nuclear translocation of NF-κB and decreases mRNA levels of IκBα and TNF-α. Cucurbitacin IIb exhibits anti-inflammatory activity and induces apoptosis. Cucurbitacin IIb is isolated from Hemsleya amabilis.
Storage Conditions
3 years -20°C powder
More Discoveries
Explore Other Products
Browse additional items from our catalog
B0055-01Q-HRP 100 µL
BAK (Apoptosis Regulator Bak, BCL2-antagonist/killer 1, BAK 1, BAK1, BAK-like, Bak NT, Bcl 2-like 7 Protein, BCL2L7, Cell Death Inhibitor 1, CDN 1, CDN1, MGC117255, MGC3887, NBak, Pro Apoptotic Protein BAK) (HRP) discontinued
Sign In for Pricing
View Details 
LV691440 1.0 µg DNA
TECR Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details 
