Isoliquiritin apioside
Product Specifications
CAS Number
120926-46-7
Synonyms
ISLA, ILA
Target
MMP
Applications
Proteases
Smiles
C1C (C (C (O1) OC2C (C (C (OC2OC3=CC=C (C=C3) C=CC (=O) C4=C (C=C (C=C4) O) O) CO) O) O) O) (CO) O
Molecular Formula
C26H30O13
Additionnal Information
Isoliquiritin apioside (ISLA, ILA), a component isolated from Glycyrrhizae radix rhizome (GR), significantly decreases PMA-induced increases in matrix metalloproteinase (MMP) activities and suppresses PMA-induced activation of mitogen-activated protein kinase (MAPK) and NF-κB. Isoliquiritin apioside possesses anti-metastatic and anti-angiogenic abilities in malignant cancer cells and ECs, with no cytotoxicity.
Storage Conditions
3 years -20°C powder
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