TC-E 5003
Product Specifications
CAS Number
17328-16-4
Synonyms
NSC 30176
Target
PRMT
Applications
Epigenetics
Smiles
ClCC (=O) NC1=CC=C (C=C1) [S] (=O) (=O) C2=CC=C (NC (=O) CCl) C=C2
Molecular Formula
C16H14Cl2N2O4S
Additionnal Information
TC-E 5003 (NSC 30176, Compound 2e) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) with IC50 of 1.5 μM. TC-E 5003 modulates the lipopolysaccharide (LPS) -induced AP-1 and NF-κB signaling pathways and can possibly be further developed as an anti-inflammatory compound.
Storage Conditions
3 years -20°C powder
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