SR-717 lithium
Product Specifications
CAS Number
2375421-09-1
Target
STING
Applications
Immunology & Inflammation
Smiles
[Li]OC (=O) C1=C (NC (=O) C2=NN=C (C=C2) [N]3C=CN=C3) C=C (F) C (=C1) F
Molecular Formula
C15H8F2LiN5O3
Additionnal Information
SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6235581-01 0.1 mL
STAT3 (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF, FLJ20882, MGC16063) (MaxLight 750)
Sign In for Pricing
View Details MBS6235581-02 5x 0.1 mL
STAT3 (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF, FLJ20882, MGC16063) (MaxLight 750)
Sign In for Pricing
View Details 