Danicopan
Product Specifications
CAS Number
1903768-17-1
Synonyms
ACH-4471, ACH-0144471, ACH-CFDIS, ALXN 2040
Target
Complement System
Applications
Immunology & Inflammation
Smiles
CC1=NC=C (C=N1) C2=CC3=C (C=C2) N (N=C3C (=O) C) CC (=O) N4CC (CC4C (=O) NC5=NC (=CC=C5) Br) F
Molecular Formula
C26H23BrFN7O3
Additionnal Information
Danicopan is a potent, selective and orally active inhibitor of factor D with Kd of 0.54 nM for human Factor D. Danicopan inhibits alternative pathway of complement (APC) activity, and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
Storage Conditions
3 years -20°C powder
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