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Spastazoline

Product Specifications

CAS Number

2351882-11-4

Target

Others

Applications

Others

Smiles

CC (C) C1CN (CCN1) C2=NC3=C (C=CN3) C (=N2) NC4=NNC (=C4) C (C) (C) C

Molecular Formula

C20H30N8

Additionnal Information

Spastazoline is a potent, cell-permeable and selective spastin (a microtubule-severing AAA (ATPases associated with diverse cellular activities) protein) inhibitor with IC50 of 99 nM for Human spastin. Spastazoline does not inhibit ATPase activity of a recombinant human VPS4 (another AAA protein required for intercellular bridge disassembly) .

Storage Conditions

3 years -20°C powder

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