PZ-2891
Product Specifications
CAS Number
2170608-82-7
Target
Others
Applications
Others
Smiles
CC (C) C1=CC=C (C=C1) CC (=O) N2CCN (CC2) C3=NN=C (C=C3) C#N
Molecular Formula
C20H23N5O
Additionnal Information
PZ-2891 is a selective, orally active and brain-penetrant pantothenate kinase (PANK) modulator that acts as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits PANK with IC50 of 40.2 nM, 0.7 nM and 1.3 nM for hPANK1β, hPANK2, and hPANK3, respectively.
Storage Conditions
3 years -20°C powder
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