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Oncrasin-1

Product Specifications

CAS Number

75629-57-1

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

C1=CC=C2C (=C1) C (=CN2CC3=CC=C (C=C3) Cl) C=O

Molecular Formula

C16H12ClNO

Additionnal Information

Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills various human lung cancer cells with K-Ras mutations. Oncrasin-1 drives abnormal aggregation of protein kinase C iota (PKCι) in nucleus of sensitive cells but not in resistant cells.

Storage Conditions

3 years -20°C powder

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