AUDA
Product Specifications
CAS Number
479413-70-2
Target
Epoxide Hydrolase
Applications
Metabolism
Smiles
C1C2CC3CC1CC (C2) (C3) NC (=O) NCCCCCCCCCCCC (=O) O
Molecular Formula
C23H40N2O3
Additionnal Information
AUDA (compound 43) is a potent inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of MMP-9, IL-1β, TNF-α and TGF-β. AUDA downregulates Smad3 and p38 signaling pathways.
Storage Conditions
3 years -20°C powder
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