TP0463518
Product Specifications
CAS Number
1558021-37-6
Target
HIF
Applications
Angiogenesis
Smiles
C1CN (C (=O) C (=C1O) C (=O) NCC (=O) O) CC2=CN=C (C=C2) OC3=CC=C (C=C3) Cl
Molecular Formula
C20H18ClN3O6
Additionnal Information
TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively.
Storage Conditions
3 years -20°C powder
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