Tubastatin A TFA
Product Specifications
CAS Number
1239262-52-2
Synonyms
Tubastatin A trifluoroacetate salt
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CN1CCC2=C (C1) C3=CC=CC=C3N2CC4=CC=C (C=C4) C (=O) NO.C (=O) (C (F) (F) F) O
Molecular Formula
C22H22F3N3O4
Additionnal Information
Tubastatin A TFA (Tubastatin A trifluoroacetate salt) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold) . Tubastatin A promotes autophagy and increases apoptosis.
Storage Conditions
3 years -20°C powder
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