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NS 1738

Product Specifications

CAS Number

501684-93-1

Synonyms

NSC 213859

Target

AChR

Applications

Neuronal Signaling

Smiles

C1=CC (=C (C=C1C (F) (F) F) NC (=O) NC2=C (C=CC (=C2) Cl) O) Cl

Molecular Formula

C14H9Cl2F3N2O2

Additionnal Information

NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR), with respect to positive modulation of Xenopus laevis oocyte α7 nAChR with EC50 of 3.4 μM, as well as a comparable efficacy at the rat α7 nAChR with EC50 of 3.9 μM.

Storage Conditions

3 years -20°C powder

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