CBL0137
Product Specifications
CAS Number
1197996-80-7
Synonyms
Curaxin-137, CBL-C137, CBLC137
Target
NF-κB
Applications
NF-κB
Smiles
CC (C) NCCN1C2=C (C=C (C=C2) C (=O) C) C3=C1C=CC (=C3) C (=O) C
Molecular Formula
C21H24N2O2
Additionnal Information
CBL0137 (Curaxin-137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF-κB and activates p53 with EC50 of 0.47 μM and 0.37 μM, respectively.
Storage Conditions
3 years -20°C powder
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