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Purvalanol B

Product Specifications

CAS Number

212844-54-7

Synonyms

NG 95

Target

CDK

Applications

Cell Cycle

Smiles

CC (C) C (CO) NC1=NC (=C2C (=N1) N (C=N2) C (C) C) NC3=CC (=C (C=C3) C (=O) O) Cl

Molecular Formula

C20H25ClN6O3

Additionnal Information

Purvalanol B (NG-95) is a potent and selective inhibitor of cyclin-dependent kinase (CDK) with IC50 of 6 nM, 6 nM, 9 nM and 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively.

Storage Conditions

3 years -20°C powder

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