Sulfatinib
Product Specifications
CAS Number
1308672-74-3
Synonyms
HMPL-012, Surufatinib
Target
CSF-1R
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC2=C (N1) C=CC (=C2) OC3=NC (=NC=C3) NC4=CC=CC (=C4) CS (=O) (=O) NCCN (C) C
Molecular Formula
C24H28N6O3S
Additionnal Information
Sulfatinib is a potent and highly selective tyrosine kinase inhibitor against VEGFR1, VEGFR2, VEGFR3, FGFR1 and CSF1R with IC50 of 2 nM, 24 nM, 1 nM, 15 nM and 4 nM, respectively. Sulfatinib shows encouraging antitumor activity and manageable toxicities in patients with advanced NETs.
Storage Conditions
3 years -20°C powder
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