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Olitigaltin (TD-139)

Product Specifications

CAS Number

1450824-22-2

Synonyms

GB0-139

Target

Galectin

Applications

Immunology & Inflammation

Smiles

C1=CC (=CC (=C1) F) C2=CN (N=N2) C3C (C (OC (C3O) SC4C (C (C (C (O4) CO) O) N5C=C (N=N5) C6=CC (=CC=C6) F) O) CO) O

Molecular Formula

C28H30F2N6O8S

Additionnal Information

Olitigaltin (TD-139, GB0-139) is a potent and selective inhibitor of galectin-3 with Kd of 0.036 μM over galectin-1 and galectin-7 with Kd of 2.2 μM and 32 μM, respectively. TD-139 is used potentially for the treatment of idiopathic pulmonary fibrosis (IPF) .

Storage Conditions

3 years -20°C powder

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