ML216
Product Specifications
CAS Number
1430213-30-1
Synonyms
CID-49852229
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1=CC (=C (C=C1NC (=O) NC2=NN=C (S2) C3=CC=NC=C3) C (F) (F) F) F
Molecular Formula
C15H9F4N5OS
Additionnal Information
ML216 (CID-49852229) is a potent and selective inhibitor of the DNA unwinding activity of BLM (Bloom’s syndrome protein) with antitumor activity. ML216 inhibits helicases with IC50 of 0.97 μM and 2.98 μM for BLM636-1298 and BLMfull-length, respectively.
Storage Conditions
3 years -20°C powder
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