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SC-43

Product Specifications

CAS Number

1400989-25-4

Target

Phosphatase

Applications

Metabolism

Smiles

C1=CC (=CC (=C1) OC2=CC=C (C=C2) C#N) NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F

Molecular Formula

C21H13ClF3N3O2

Additionnal Information

SC-43, a sorafenib derivative, is an agonist of Src-homology protein tyrosine phosphatase-1 (SHP-1/PTPN6) and reduces liver fibrosis. SC-43 reduces p-STAT3 and induces apoptosis with anti-tumor activity.

Storage Conditions

3 years -20°C powder

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