SAR-20347
Product Specifications
CAS Number
1450881-55-6
Target
JAK
Applications
Angiogenesis
Smiles
C1COCCN1C (=O) C2=CC=C (C=C2) NC3=C (N=C (O3) C4=C (C=CC=C4Cl) F) C (=O) N
Molecular Formula
C21H18ClFN4O4
Additionnal Information
SAR-20347 is a potent inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediated IL-12 and IFN-α signaling.
Storage Conditions
3 years -20°C powder
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