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AF-353

Product Specifications

CAS Number

865305-30-2

Synonyms

Ro-4

Target

P2 Receptor

Applications

Neuronal Signaling

Smiles

CC (C) C1=CC (=C (C=C1OC2=CN=C (N=C2N) N) I) OC

Molecular Formula

C14H17IN4O2

Additionnal Information

AF-353 (Ro-4) is a potent, selective and orally bioavailable antagonist of P2X3 receptor and P2X2/3 receptor with pIC50 of 8.06, 8.05 and 7.41 for human P2X3, rat P2X3 and human P2X2/3, respectively.

Storage Conditions

3 years -20°C powder

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