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KAN0438757

Product Specifications

CAS Number

1451255-59-6

Target

PFKFB

Applications

Apoptosis

Smiles

C1=CC (=CC (=C1) S (=O) (=O) NC2=CC (=C (C=C2) C (=O) OCCO) O) C3=C (C=CC (=C3) F) O

Molecular Formula

C21H18FNO7S

Additionnal Information

KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3) with IC50 of 0.19 μM and 3.6 μM for PFKFB3 and PFKFB4, respectively.

Storage Conditions

3 years -20°C powder

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