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EGFR Inhibitor

Product Specifications

CAS Number

879127-07-8

Synonyms

EGFR-IN-12

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

C1CC1C (=O) NC2=CC=CC (=C2) NC3=NC=NC (=C3) NC4=CC=CC (=C4) C (F) (F) F

Molecular Formula

C21H18F3N5O

Additionnal Information

EGFR inhibitor, a cell permeable, 4,6-disubstituted pyrimidine compound, is a highly selevtive inhibitor of EGFR kinase with IC50 of 21 nM. EGFR inhibitor directly depolymerizes microtubules and is used as a chemical probe to investigate both the EGFR pathway and microtubule dynamics.

Storage Conditions

3 years -20°C powder

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