DMX-5084
Product Specifications
CAS Number
2306178-56-1
Target
MAP4K
Applications
MAPK
Smiles
COCCOC1=CC=C (C=C1) C2=CN (C3=C2C (=O) NC=N3) C4=CC=CC=C4
Molecular Formula
C21H19N3O3
Additionnal Information
DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.
Storage Conditions
3 years -20°C powder
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