TRi-1
Product Specifications
CAS Number
246020-68-8
Synonyms
HUN20688, TXNRD1 inhibitor 1
Target
Thioredoxin Reductase
Applications
Metabolism
Smiles
COC1=NC (=C (C=C1) [N+] (=O) [O-]) S (=O) (=O) C2=CC=C (C=C2) Cl
Molecular Formula
C12H9ClN2O5S
Additionnal Information
TRi-1 (HUN20688, TXNRD1 inhibitor 1) is a potent, specific and irreversible cytosolic thioredoxin reductase 1 (TXNRD1) inhibitor with IC50 of 12 nM. TRi-1 exhibits anti-cancer activity while having little mitochondrial toxicity.
Storage Conditions
3 years -20°C powder
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