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TRi-1

Product Specifications

CAS Number

246020-68-8

Synonyms

HUN20688, TXNRD1 inhibitor 1

Target

Thioredoxin Reductase

Applications

Metabolism

Smiles

COC1=NC (=C (C=C1) [N+] (=O) [O-]) S (=O) (=O) C2=CC=C (C=C2) Cl

Molecular Formula

C12H9ClN2O5S

Additionnal Information

TRi-1 (HUN20688, TXNRD1 inhibitor 1) is a potent, specific and irreversible cytosolic thioredoxin reductase 1 (TXNRD1) inhibitor with IC50 of 12 nM. TRi-1 exhibits anti-cancer activity while having little mitochondrial toxicity.

Storage Conditions

3 years -20°C powder

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