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6-OAU

Product Specifications

CAS Number

83797-69-7

Synonyms

GTPL5846, 6-n-octylaminouracil

Target

GPR

Applications

GPCR & G Protein

Smiles

CCCCCCCCNC1=CC (=O) NC (=O) N1

Molecular Formula

C12H21N3O2

Additionnal Information

6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay. 6-OAU (GTPL5846, 6-n-octylaminouracil) increases [35S]GTPγS incorporated in Sf9 cell membranes expressing human GPR84-Gαi fusion protein with EC50 of 512 nM.

Storage Conditions

3 years -20°C powder

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