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RO8994

Product Specifications

CAS Number

1309684-94-3

Target

MDM2/MDMX

Applications

Apoptosis

Smiles

CC (C) (C) CC1C2 (C (C (N1) C (=O) NC3=C (C=C (C=C3) C (=O) N) OC) C4=C (C (=CC=C4) Cl) F) C5=C (C=C (C=C5) Cl) NC2=O

Molecular Formula

C31H31Cl2FN4O4

Additionnal Information

RO8994 is a potent and selective small-molecule MDM2 inhibitor with IC50 values of 5 nM in HTRF binding assays and 20 nM in MTT proliferation assays, respectively.

Storage Conditions

3 years -20°C powder

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