PTP1B-IN-2
Product Specifications
CAS Number
1919853-46-5
Synonyms
MDK3465, Ptp1B-In-2, Compound P6
Target
Phosphatase
Applications
Metabolism
Smiles
CC1=CC=C (C=C1) COC2=C (C=C (C=C2) N (CC3=CC=C (C=C3) N (CC (=O) OC) S (=O) (=O) C) S (=O) (=O) CC4=CC=CC=C4) C (=O) OC
Molecular Formula
C34H36N2O9S2
Additionnal Information
PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose uptake.
Storage Conditions
3 years -20°C powder
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