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Pemigatinib

Product Specifications

CAS Number

1513857-77-6

Synonyms

INCB054828

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CCN1C2=C3C=C (NC3=NC=C2CN (C1=O) C4=C (C (=CC (=C4F) OC) OC) F) CN5CCOCC5

Molecular Formula

C24H27F2N5O4

Additionnal Information

Pemigatinib is an orally active and selective inhibitor of FGFR with IC50 of 0.4 nM, 0.5 nM, 1.2 nM and 30 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.

Storage Conditions

3 years -20°C powder

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