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JNJ 303

Product Specifications

CAS Number

878489-28-2

Target

Potassium Channel

Applications

Transmembrane Transporters

Smiles

CC (C) (C (=O) NC1C2CC3CC1CC (C3) (C2) NS (=O) (=O) C) OC4=CC=C (C=C4) Cl

Molecular Formula

C21H29ClN2O4S

Additionnal Information

JNJ 303 is a potent blocker of the voltage dependent IKs-channel encoded by KCNQ1/KCNE1 with IC50 of 64 nM. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP) .

Storage Conditions

3 years -20°C powder

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