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RG3039

Product Specifications

CAS Number

1005504-62-0

Synonyms

PF-06687859, PF 6687859, Quinazoline 495

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

C1CN (CCC1COC2=CC=CC3=C2C (=NC (=N3) N) N) CC4=C (C=CC=C4Cl) Cl

Molecular Formula

C21H23Cl2N5O

Additionnal Information

RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively.

Storage Conditions

3 years -20°C powder

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