IAXO-102
Product Specifications
CAS Number
1115270-63-7
Target
TLR
Applications
Immunology & Inflammation
Smiles
CCCCCCCCCCCCCCOC1C (C (OC (C1OCCCCCCCCCCCCCC) OC) CN) O
Molecular Formula
C35H71NO5
Additionnal Information
IAXO-102 is an antagonist of TLR4 targeting both MD-2 and CD14 co-receptors. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and downregulates the expression of TLR4 dependent proinflammatory proteins. IAXO-102 inhibits experimental abdominal aortic aneurysm (AAA) development.
Storage Conditions
3 years -20°C powder
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