CTX-0124143
CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton[1].
Product Specifications
CAS Number
[423731-64-0]
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ctx-0124143.html
Purity
98.84
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NNS(=O)(C1=CC=C2C=CC=CC2=C1)=O)C3=CC=CC=C3F
Molecular Formula
C17H13FN2O3S
Molecular Weight
344.36
References & Citations
[1]Duan Y, et al. Discovery of N- (2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy. Eur J Med Chem. 2023 Nov 15;260:115770.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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