ATC-324
Product Specifications
CAS Number
2925060-81-5
Target
Androgen Receptor
Applications
Endocrinology & Hormones
Additionnal Information
ATC-324 is a potent AUTOphagy-TArgeting Chimera (AUTOTAC) degrader of androgen receptor (AR) with a DC50 of 2.05 μM. It induces autophagy–lysosomal degradation of AR, reduces nuclear AR and AR-V7 activity, and causes cytotoxicity in AR-positive prostate cancer cells, making it useful for prostate cancer research.
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