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ATC-324

Product Specifications

CAS Number

2925060-81-5

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Additionnal Information

ATC-324 is a potent AUTOphagy-TArgeting Chimera (AUTOTAC) degrader of androgen receptor (AR) with a DC50 of 2.05 μM. It induces autophagy–lysosomal degradation of AR, reduces nuclear AR and AR-V7 activity, and causes cytotoxicity in AR-positive prostate cancer cells, making it useful for prostate cancer research.

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