PM534
Product Specifications
CAS Number
2446376-25-4
Target
Microtubule Associated
Applications
Cytoskeletal Signaling
Additionnal Information
PM534 is a potent microtubule-targeting agent (MTA) that binds the colchicine-binding domain (CBD) and inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. It also significantly inhibits tumor growth in mouse xenograft models of human non-small cell lung cancer.
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